The coronavirus cases have hit a record daily high in the United States with a renewed wave of infections.
Citing data from local state health authorities, 83,010 new cases were reported on Friday.
America’s Midwest continues to be the hardest-hit region of the country, with cases soaring in states like North Dakota, Montana and Wisconsin.
In Ohio, a key battleground state for the upcoming presidential election, authorities recorded their worst daily case increase for a third day running.
Others in the region, including Illinois and Indiana, also saw daily rises near or at record highs on Friday.
Meanwhile, in the south-west cases reached an all-time high in Utah, where new mandatory mask rules have been introduced in 21 counties.
Governor Gary Herbert warned that the virus’s impact had seriously impacted local hospital capacity.
US Surgeon General Jerome Adams has warned that hospital admission numbers were growing for the first time since April and July.
It comes as pharma giants AstraZeneca and Johnson & Johnson resume US vaccine trials after approval from regulators.
The World Health Organization (WHO) has also warned that countries in the Northern Hemisphere are at a “critical juncture”.
“The next few months are going to be very tough and some countries are on a dangerous track,” said director general Tedros Adhanom Ghebreyesus, speaking to reporters.