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Russian coronavirus vaccine shows signs of immune response: Medical Journal

Scientists published the first report on the Russian coronavirus vaccine, saying early tests showed signs of an immune response.

According to a report published by medical journal The Lancet said every participant developed antibodies to fight the virus and had no serious side effects.

Two trials of the vaccine, named Sputnik-V, were conducted between June and July, The Lancet paper said. Each involved 38 healthy volunteers who were given a dose of the vaccine and then a booster vaccine three weeks later.

The participants – aged between 18 and 60 – were monitored for 42 days and all of them developed antibodies within three weeks. Among the most common side effects were headaches and joint pain.




The trials were open label and not randomised, meaning the volunteers were aware they were receiving the vaccine.

Russia licensed the vaccine for local use in August, the first country to do so and before data had been published.

Experts say the trials were too small to prove effectiveness and safety.



But Moscow has hailed the results as an answer to critics. Some Western experts have raised concerns about the speed of Russia’s work, suggesting that researchers might be cutting corners.

Last month, President Vladimir Putin said the vaccine had passed all the required checks and that one of his own daughters had been given it.

A third phase of trials will involve 40,000 volunteers from “different age and risk groups,” according to the paper.

The Russian vaccine uses adapted strains of the adenovirus, a virus that usually causes the common cold, to trigger an immune response.